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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
28.18
Human Site:
S350
Identified Species:
44.29
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
S350
V
T
D
E
H
H
R
S
E
E
E
L
L
V
I
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
S350
V
T
D
E
H
H
R
S
E
E
E
L
L
V
I
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
S350
V
T
D
E
H
H
R
S
E
E
E
L
L
V
I
Dog
Lupus familis
XP_536242
380
42964
S351
V
T
N
E
H
H
R
S
E
E
E
L
L
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
S359
V
M
N
D
H
H
T
S
E
E
E
L
L
A
I
Rat
Rattus norvegicus
Q6AYK5
386
43662
S357
V
M
S
D
H
H
T
S
E
E
E
L
L
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
K361
V
T
A
S
G
Q
H
K
S
E
E
D
L
L
V
Chicken
Gallus gallus
XP_420792
364
42082
S335
V
A
G
E
H
H
K
S
E
E
D
I
L
V
I
Frog
Xenopus laevis
NP_001086609
360
41600
S331
V
S
S
E
H
H
K
S
E
K
D
L
L
I
A
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
R290
F
S
G
D
R
N
Y
R
S
E
E
E
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
Q257
E
K
Q
A
K
K
F
Q
K
R
F
D
K
Q
L
Honey Bee
Apis mellifera
XP_623803
246
28455
N222
T
I
N
N
D
T
I
N
N
A
K
K
K
K
L
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
D229
G
A
A
S
D
D
V
D
S
I
F
D
E
K
L
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
H729
H
V
K
K
V
R
T
H
G
Q
T
N
I
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
D129
K
I
L
K
T
M
K
D
K
G
A
K
K
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
100
100
86.6
N.A.
66.6
66.6
N.A.
33.3
66.6
53.3
20
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
73.3
N.A.
46.6
86.6
86.6
46.6
N.A.
13.3
26.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
7
0
0
0
0
0
7
7
0
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
20
14
7
0
14
0
0
14
20
0
0
0
% D
% Glu:
7
0
0
40
0
0
0
0
54
60
54
7
7
0
0
% E
% Phe:
7
0
0
0
0
0
7
0
0
0
14
0
0
0
7
% F
% Gly:
7
0
14
0
7
0
0
0
7
7
0
0
0
0
0
% G
% His:
7
0
0
0
54
54
7
7
0
0
0
0
0
0
0
% H
% Ile:
0
14
0
0
0
0
7
0
0
7
0
7
7
7
47
% I
% Lys:
7
7
7
14
7
7
20
7
14
7
7
14
20
14
0
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
47
67
14
27
% L
% Met:
0
14
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
20
7
0
7
0
7
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
0
7
0
7
0
0
0
14
0
% Q
% Arg:
0
0
0
0
7
7
27
7
0
7
0
0
0
0
0
% R
% Ser:
0
14
14
14
0
0
0
54
20
0
0
0
0
0
7
% S
% Thr:
7
34
0
0
7
7
20
0
0
0
7
0
0
14
0
% T
% Val:
60
7
0
0
7
0
7
0
0
0
0
0
0
27
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _